- Review Article
- Mesenchymal stem cells transplantation for neuroprotection in preterm infants with severe intraventricular hemorrhage
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So Yoon Ahn, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2014;57(6):251-256. Published online June 30, 2014
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Severe intraventricular hemorrhaging (IVH) in premature infants and subsequent posthemorrhagic hydrocephalus (PHH) causes significant mortality and life-long neurological complications, including seizures, cerebral palsy, and developmental retardation. However, there are currently no effective therapies for neonatal IVH. The pathogenesis of PHH has been mainly explained by inflammation within the subarachnoid spaces due to the hemolysis of extravasated blood after IVH. Obliterative... |
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- Case Report
- A novel PRF1 gene mutation in a fatal neonate case with type 2 familial hemophagocytic lymphohistiocytosis
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Jae Yeon Kim, Jeong Hee Shin, Se In Sung, Jin Kyu Kim, Ji Mi Jung, So Yoon Ahn, Eun Sun Kim, Ja-Young Seo, Eun-Sook Kang, Sun-Hee Kim, Hee-Jin Kim, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2014;57(1):50-53. Published online January 31, 2014
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Hemophagocytic lymphohistiocytosis (HLH) occurs in the primary form (genetic or familial) or secondary form (acquired). The familial form of HLH (FHL) is a potentially fatal autosomal recessive disorder that occurs because of constitutional defects in cell-mediated cytotoxicity. Here, we report a fatal neonatal case of type 2 FHL (FHL2) that involved a novel frameshift mutation. Clinically, the newborn presented with... |
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- Retropharyngeal abscess coinfected with Staphylococcus aureus and Mycobacterium tuberculosis after rhinoviral infection in a 1-month-old infant
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Jeong Hee Shin, Se In Sung, Jin Kyu Kim, Ji Mi Jung, Eun Sun Kim, Soo Han Choi, Yae Jean Kim, Kang Mo Ahn, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2013;56(2):86-89. Published online February 25, 2013
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A retropharyngeal abscess is a rare disease entity in young infants but can develop after nasopharyngeal viral infection. Group B Streptococcus and Staphylococcus aureus are the most common pathogens in young infants, however, Mycobacterium tuberculosis is very rare. We report the case of retropharyngeal abscess and coinfection with S. aureus and M. tuberculosis in a very young infant presenting with... |
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- Sequential magnetic resonance spectroscopic changes in a patient with nonketotic hyperglycinemia
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Ji Hun Shin, So Yoon Ahn, Jeong Hee Shin, Se In Sung, Ji Mi Jung, Jin Kyu Kim, Eun Sun Kim, Hyung Doo Park, Ji Hye Kim, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2012;55(8):301-305. Published online August 23, 2012
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Nonketotic hyperglycinemia (NKH) is a rare inborn error of amino acid metabolism. A defect in the glycine cleavage enzyme system results in highly elevated concentrations of glycine in the plasma, urine, cerebrospinal fluid, and brain, resulting in glycine-induced encephalopathy and neuropathy. The prevalence of NKH in Korea is very low, and no reports of surviving patients are available, given the... |
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- Original Article
- Neuroprotective effects of L-carnitine against oxygen-glucose deprivation in rat primary cortical neurons
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Yu Jin Kim, Soo Yoon Kim, Dong Kyung Sung, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2012;55(7):238-248. Published online July 17, 2012
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Purpose Hypoxic-ischemic encephalopathy is an important cause of neonatal mortality, as this brain injury disrupts normal mitochondrial respiratory activity. Carnitine plays an essential role in mitochondrial fatty acid transport and modulates excess acyl coenzyme A levels. In this study, we investigated whether treatment of primary cultures of rat cortical neurons with L-carnitine was able to prevent neurotoxicity resulting from oxygen-glucose deprivation... |
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- Case Report
- Idiopathic severe hypermagnesemia in an extremely low birth weight infant on the first day of life
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Hye Sun Hyun, Hyun Sin Choi, Jin Kyu Kim, So Yoon Ahn, Hey Soo Yoo, Eun Sun Kim, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2011;54(7):310-312. Published online July 31, 2011
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A preterm female infant born at 27 weeks of gestation with a birth weight of 990 g developed acute hypotonia, apnea, hypotension and bradycardia mimicking septic shock syndrome at 14h after birth. Laboratory tests indicated a severe hypermagnesemia of 45 mg/dL. The renal function, complete blood count and maternal blood concentrations of magnesium were normal, and the blood cultures were... |
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- Original Article
- Outcomes of small for gestational age micropremies depending on how young or how small they are
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Hee Joon Yu, Eun Sun Kim, Jin Kyu Kim, Hye Soo Yoo, So Yoon Ahn, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2011;54(6):246-252. Published online June 30, 2011
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Purpose The outcomes of small for gestational age (SGA) infants especially in extremely low birth weight infants (ELBWIs) are controversial. This study evaluated the mortality and morbidity of ELBWIs, focusing on whether or not they were also SGA. MethodsThe medical records of 415 ELBWIs (birth weight <1,000 g), who were inborn and admitted to the Samsung Medical Center neonatal intensive care unit... |
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- Effect of SynagisⓇ (palivizumab) prophylaxis on readmission due to
respiratory syncytial virus in very low birth weight infants
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Soo Kyoung Park, Yu Jin Jung, Hye Soo Yoo, So Yoon Ahn, Hyun Joo Seo, Seo Heui Choi, Myo Jing Kim, Ga Won Jeon, Soo Hyun Koo, Kyung-Hoon Lee, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2010;53(3):358-363. Published online March 15, 2010
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Purpose : The aim of this study was to determine the efficacy of SynagisⓇ (palivizumab) in reducing the respiratory syncytial virus (RSV) readmission rate in very low birth weight infants (VLBWI ) and the subgroup that showed the most effective vaccination.
Methods : We enrolled 350 VLBWI who had been discharged alive from the neonatal intensive care unit of Samsung Medical... |
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- Analysis of prognostic factors of laparotomy for necrotizing enterocolitis in extremely low birth weight infants
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Jin Kyu Kim, Yi Sun Kim, Hye Soo Yoo, So Yoon Ahn, Hyun ju Seo, Seo Heui Choi, Soo Kyung Park, Yu Jin Jung, Myo Jing Kim, Ga Won Jeon, Soo Hyun Koo, Kyung-Hoon Lee, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2010;53(2):167-172. Published online February 15, 2010
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Purpose : With improved survival of extremely low birth weight infants (ELBWI), there is an increase in the incidence of necrotizing enterocolitis (NEC) requiring laparotomy, and the risk of morbidity and mortality in these ELBWI is increased. Thus, we determined the prognostic factors in ELBWI who underwent laparotomy for NEC.
Methods : We retrospectively reviewed the medical records of 35 ELBWI... |
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- Clinical course and prognosis of hemodynamically significant congenital heart defects in very low birth weight infants
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Hye Soo Yoo, Ji Eun Kim, Soo Kyoung Park, Hyun Ju Seo, Yoo Jin Jeong, Seo Heui Chio, Soo In Jeong, Sung Hoon Kim, Ji Hyuk Yang, June Huh, Yun Sil Chang, Tae Gook Jun, I Seok Kang, Won Soon Park, Pyo Won Park, Heung Jae Lee
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Clin Exp Pediatr. 2009;52(4):481-487. Published online April 15, 2009
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Purpose : This study investigated the clinical course and prognostic factor of very low birth weight infants (VLBWI) with hemodynamically significant congenital heart defects (CHDs).
Methods : Medical records of 1,098 VLBWI with birth weight <1,500 g who had been admitted to the neonatal intensive care unit of Samsung Medical Center from October 1994 to December 2007 were reviewed retrospectively. The... |
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- Gastrointestinal surgery in very low birth weight infants : Clinical characteristics
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Ji Eun Kim, Hye Soo Yoo, Hea Eun Kim, Soo Kyoung Park, Yoo Jin Jeong, Seo Heui Choi,, Hyun Joo Seo, Yun Sil Chang, Jeong Meen Seo, Won Soon Park, Suk Koo Lee
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Clin Exp Pediatr. 2009;52(3):295-302. Published online March 15, 2009
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Purpose : To report our experience of gastrointestinal (GI) operations (OP) performed in very low birth weight infants (VLBWI) and to evaluate their clinical characteristics.
Methods : Among the 1,117 VLBWI admitted to the SMC neonatal intensive care unit from November 1994 to February 2007, the medical records of 37 infants who underwent GI OP (except inguinal hernia OP) and 1,080... |
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- Case Report
- A case of pulmonary vascular air embolism in a very-low-birth-weight infant with massive hydrops
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Myo Jing Kim, Hee Joon Yu, Cha Gon Lee, Soo Kyoung Park, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2009;52(12):1392-1395. Published online December 15, 2009
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Pulmonary vascular air embolism is a rare and, universally, almost a fatal complication of positive pressure ventilation in newborn infants. Here, we report a case of this unusual complication in a very-low-birth-weight infant who showed the clinical and radiological features of this complication along with pulmonary hypoplasia and massive hydrops. The possible pathogenesis has been discussed and a brief review... |
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- Original Article
- Rotavirus-associated neonatal necrotizing enterocolitis
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Hyun Joo Seo, Yu Jin Jung, Soo Kyung Park, Seo Hui Choi, Ji Hyuk Lee, Myo Jing Kim, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2009;52(1):56-60. Published online January 15, 2009
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Purpose : This study aimed to test whether rotavirus-associated necrotizing enterocolitis (RV+NEC) produced different clinical findings or outcomes from those of non-rotavirus necrotizing enterocolitis (RV-NEC).
Methods : Eight patients from the RV+NEC group and 22 patients from the RV-NEC group diagnosed with modified Bell stage II or higher NEC were selected for this study. Fecal specimens from all infants were tested... |
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- Periventricular leukomalacia induced by in utero clamping of pregnant rat aorta in fetal rats
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Yun Sil Chang, Dong Kyung Sung, Saem Kang, Soo Kyung Park, Yu Jin Jung, Hyun Joo Seo, Seo Heui Choi, Won Soon Park
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Clin Exp Pediatr. 2008;51(8):874-878. Published online August 15, 2008
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Purpose : This study was undertaken to develop an animal model of periventricular leukomalacia (PVL) induced by in utero clamping of pregnant rat aorta in fetal rats.
Methods : A timed pregnanct Sprague-Dawley rat on embryonic day 21 just prior to delivery was sedated and anesthetized, and a Harvard ventilator for small animals was applied. Following laparotomy, the maternal aorta was... |
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- Improved survival rate with decreased neurodevelopmental disability in extreme immaturity
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Ga Won Jeon, Myo Jing Kim, Sung Shin Kim, Jae Won Shim, Yun Sil Chang, Won Soon Park, Mun Hyang Lee
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Clin Exp Pediatr. 2007;50(11):1067-1071. Published online November 15, 2007
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Purpose : The aim of this study was to determine whether improved survival of extremely low birth weight infants (ELBWI) was associated with decreased neurodevelopmental disability later in life, and also to identify the factors influencing this disability.
Methods : ELBWI admitted to the neonatal intensive care unit of Samsung Medical Center, survived, and followed up until the corrected age... |
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- Effect of prophylactic indomethacin in extremely low birth weight infants
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Bo Lyun Lee, Su Jin Kim, Soo Hyun Koo, Ga Won Jeon, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2006;49(9):959-965. Published online September 15, 2006
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Purpose : The purpose of this study was to investigate the effect of prophylactic indomethacin on reduction of patent ductus arteriosus(PDA) and intraventricular hemorrhage(IVH) in extremely low birth weight infants(ELBWI).
Methods : Retrospective review of 84 ELBWI who were admitted to our neonatal intensive care unit from June 2004 to April 2006 was performed. Patients were divided into prophylactic group(n=28) and... |
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- Effects of NG-monomethyl-L-arginine and L-arginine on cerebral hemodynamics and energy metabolism during reoxygenation-reperfusion after cerebral hypoxia-ischemia in newborn piglets
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Sun Young Ko, Saem Kang, Yun Sil Chang, Eun Ae Park, Won Soon Park
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Clin Exp Pediatr. 2006;49(3):317-325. Published online March 15, 2006
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Purpose : This study was carried out to elucidate the effects of nitric oxide synthase(NOS) inhibitor, NG-monomethyl-L-arginine(L-NMMA) and nitric oxide precursor, L-arginine(L-Arg) on cerebral hemodynamics and energy metabolism during reoxygenation-reperfusion(RR) after hypoxia- ischemia(HI) in newborn piglets.
Methods : Twenty-eight newborn piglets were divided into 4 groups; Sham normal control(NC), experimental control(EC), L-NMMA(HI & RR with L-NMMA), and L-Arg(HI & RR... |
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- Outcomes and Management of Fetal Infants with Birth Weight Below 500 g at a Tertiary Center
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Yun Sil Chang, Yu Jin Kim, Soo Hyun Koo, Jang Hoon Lee, Jong Hee Hwang, Chang Won Choi, Jae Won Shim, Sung Shin Kim, Sun Young Ko, Eun Kyung Lee, Won Soon Park
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Clin Exp Pediatr. 2005;48(9):939-945. Published online September 15, 2005
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Purpose : The purpose of this study was to report outcome of fetal infants with birth weight below 500 g known as lower limit of viability and to evaluate treatment characteristics and short-term morbidity of their survivors.
Methods : We retrospectively analyzed the medical records of all fetal infants with birth weight below 500 g who were delivered at Samsung Medical... |
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- The Effects of Early Enteral Feeding in Extremely Low Birth-Weight Infants
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Ga Won Jeon, Sung Eun Park, Chang Won Choi, Jong Hee Hwang, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2005;48(7):711-715. Published online July 15, 2005
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Purpose : With the recent improved survival of extremely low birth weight infants(ELBWI), enteral feeding has become a major issue. This study investigates the effects of early enteral feeding in ELBWI on their morbidity, duration of hospitalization, and mortality.
Methods : ELBWI admitted to the neonatal intensive care unit at Samsung Medical Center from November 1994 to April 2004 who survived... |
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- Near-Infrared Spectroscopy for Monitoring Cerebral Hemodynamics in Hyperbilirubinemia-induced Newborn Piglets
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Jong Hee Hwang, Chang Won Choi, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2005;48(6):649-654. Published online June 15, 2005
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Purpose : The present study examined how changes in cerebral hemodynamics in newborn piglets with bilirubin infusion can be evaluated by near infrared sepctroscopy(NIRS).
Methods : Seventeen newborn piglets were randomly divided into the following three experimental groups : six in the control group(CG); seven in the bilirubin infusion group(BG), and four in the bilirubin infusion with 7-nitroindazole group(NG). To... |
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- Extubation Time by Birth Weight and the Predictors for Success/Failure at the First Extubation in Extremely Low Birth Weight Infants
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Chang Won Choi, Sung Eun Park, Ga Won Jeon, Eun Jung Yoo, Jong Hee Hwang, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2005;48(5):488-494. Published online May 15, 2005
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Purpose : To outline the aspects of extubation by birth weight and find the predictors for success/ failure at the first extubation in extremely low birth weight infants.
Methods : One hundred thirteen extremely low birth weight infants(<1,000 g) who were admitted to NICU at Samsung Seoul Hospital between Jan. 2000 and Jun. 2004 were enrolled. Clinical characteristics that are thought... |
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- Single Cell Dissociation Methods for Flow Cytometric Cell Death Analysis of Hypoxia-Ischemia Injured Newborn Rat Pup Brain
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Jong Hee Hwang, Dong Kyung Sung, Chang Won Choi, Saem Kang, Yun Sil Chang, Won Soon Park, Munhyang Lee
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Clin Exp Pediatr. 2005;48(5):545-550. Published online May 15, 2005
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Purpose : Newborn brain tissue has to be dissociated into a single cell suspension for flow cytometric analysis of cell death during hypoxia-ischemia. Thus the development of a method to dissociate cells from the brain tissue with least damage and maintenance of membrane and antigen integrity remains the challenge for the in vivo application of this technique. We evaluated the... |
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- Evaluation of Perinatal and Management Factors Associated with Improved Survival in Extremely Low Birth Weight Infants
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Sung Eun Park, Ga Won Jeon, Chang Won Choi, Jong Hee Hwang, Soo Hyun Koo, Yu Jin Kim, Chang Hoon Lee, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2005;48(12):1324-1329. Published online December 15, 2005
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Purpose : The aim of this study was to evaluate recent improvements in the survival rate of extremely low birth weight (ELBW) infants and to identify perinatal and management factors that are associated with improved survival.
Methods : Two groups of ELBW infants who were admitted to our neonatal intensive care unit (NICU) during two distinct eras : November 1994-December... |
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- Etiology, Management, and Prognosis of Severe Hyperbilirubinemia (Serum Bilirubin Level=25 mg/dL) in Newborn
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Jong Hee Hwang, Ji Hyun Lee, Yu Jin Kim, Su Hyun Koo, Jang Hun Lee, Chang Won Cho, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2005;48(10):1102-1106. Published online October 15, 2005
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Purpose : The present study examined the etiology, management, and the difference of prognosis according to methodology of treatment in severe hyperbilirubinemia with total serum bilirubin levels of more than 25 mg/dL.
Methods : Medical records of severe hyperbilirubiemia in newborns(serum level=25 mg/dL) admitted to the NICU of Samsung Medical Center between October 1994 and June 2004 were reviewed retrospectively. Infants... |
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- Original Article
- Change in the Limit of Viability of Fetal Infants
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Chang Won Choi, Jong Hee Hwang, Jae Won Shim, Sung Sin Kim, Sun Young Ko, Eun Kyung Lee, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2003;46(12):1194-1199. Published online December 15, 2003
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Purpose : To determine the change in the limit of viability in fetal infants and the incidence of major complications in neonatal intensive care unit(NICU) at Samsung Medical Center(SMC).
Methods : Sevety-three infants weighing less than 800 g at birth and 117 infants born earlier than 27 weeks gestational age, who were admitted to NICU at SMC between November 1994... |
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- Changes in the Outcomes of Very Low Birth Weight Infants
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Shung Shin Kim, Moon Hee Kim, Jae Won Shin, Sun Young Ko, Eun Kyung Lee, Yun Sil Chang, I Seok Kang, Won Soon Park, Mun Hyang Lee, Sang Il Lee, Heung Jae Lee
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Clin Exp Pediatr. 2002;45(7):828-835. Published online July 15, 2002
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Purpose : The outcomes of infants weighing less than 1,500 gm(very low birth weight infant : VLBWI) reflect recent progress in neonatal intensive care. In this study, we analyzed changes over time in survival rate and morbidity of VLBWIs during the past seven years.
Methods : A retrospective review of medical records was analyzed for VLBWIs admitted to the neonatal intensive... |
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- Case Report
- Zellweger Syndrome : First Confirmed Neonatal Case in Korea
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Sung Sin Kim, Yun Hwa An, Yun Sil Chang, Dong Kyu Jin, Won Soon Park, Moon Hang Lee, Jong Won Kim, Hye Kyoung Yoon, Bo Kyoung Kim
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Clin Exp Pediatr. 2001;44(6):694-698. Published online June 15, 2001
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We describe below a case of Zellweger syndrome case with facial dysmorphism, profound hypotonia, and hepatomegaly. He died at the age of 2 months. Zellweger syndrome is a disease marked by the absence of hepatic and renal peroxisomes. Because peroxisomes have many vital anabolic and catabolic functions within the cell, their absence results in profound cellular dysfunction. A biochemical study... |
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- Original Article
- Neonatal Systemic Candidiasis : Comparison of Albicans and Parapsilosis Infection
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Jung Mie Han, Ho Young Lee, Mi Jeong Kang, Sun Young Ko, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2000;43(8):1052-1058. Published online August 15, 2000
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Purpose : Systemic Candidiasis has become an increasingly important cause of morbidity and mortality in NICU infants. Severe infections caused by non-albicans Candida species have been increasingly reported in NICU infants. The purpose of the present study was to compare relative severity, mortality rates for C. albicans(CA) and C. parapsilosis(CP) infections in our NICU.
Methods : This study included 16 infants... |
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- Effects of Partial Liquid Ventilation on Gas Exchange, Hemodynamics, and Pulmonary Function in Newborn Piglet with Respiratory Distress
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Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 2000;43(11):1430-1439. Published online November 15, 2000
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Purpose : To evaluate gas exchange, hemodynamics and pulmonary function during partial liquid ventilation(PLV) using PFC(perfluorodecalin), compared with conventional gas ventilation in newborn piglets with saline lavage-induced respiratory distress.
Methods : In a total of 16 instrumented and ventilated piglets, acute respiratory distress(below 70 mmHg of PaO2 at FiO2 1.0) was induced by repeated saline pulmonary lavage. The piglets were randomized... |
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- High Frequency Oscillatory Ventilation as a Rescue Therapy of Severe Neonatal Respiratory Failure
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Eun Kyung Lee, Yun Sil Chang, Won Soon Park
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Clin Exp Pediatr. 1998;41(4):456-465. Published online April 15, 1998
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Purpose : High frequency oscillatory ventilation(HFOV) using suprathysiologic ventilatory frequency is a new therapeutic technique, which has a improved survival and reduced complication of newborn infants suffering from severe respiratory failure. The aim of this study was to assess the efficacy of HFOV as a rescue therapy for infants with severe respiratory failure and to compare the treatment results... |
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- Hemodynamic Effect of Nitric Oxide Inhalation in the Acute Hypoxic Pulmonary Hypertension Induced Newborn Piglet
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Yun Cil Chang, Won Soon Park, Jung-Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1997;40(10):1394-1409. Published online October 15, 1997
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Purposes : Nitric oxide(NO) is classified as toxic gas in native states, but in most biologic
systems NO acts as a messenger molecule. NO is known as endothelium derived relaxing factor
that modulates tone of vascular smooth muscle. Inhaled NO has been reported to act as a selective
pulmonary vasodilator and we expect that NO inhalation can be used as a successful treatment
modality... |
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- Genital Mycoplasmasin the Newborn Infants: Colonization, Prevalence and Clinical Significance
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Yun Sil Chang, Sung Gwon Kim, Beyong Il Kim, Won Soon Park, Bo Hyun Yoon, Eui Chong Kim, Jung-Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1996;39(8):1084-1094. Published online August 15, 1996
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Purpose : The genital mycoplasmas: Ureaplasma urealyticum and Mycoplasma hominis have
recently assumed an increasing importance as neonatal pathogens especially in preterm infants.
The aim of the present study was to determine the prevalence of infections with these organisms
in newborn infants who were admitted in Neonatal Intensive Care Unit(NICU) and who were
suspected having infection in newborn nursery
Methods : Sixty four inborns who... |
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- Case Report
- Two Cases of Nitric Oxide Inhalation for Treatment of Severe Pulmonary Hypertension after Surgical Repair of Congenital Diaphragmatic Hernia
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Yun Sil Chang, I-Seok Kang, Won Soon Park, Suk Koo Lee, Hun Hahk Kim, Heung Jae Lee
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Clin Exp Pediatr. 1996;39(11):1611-1619. Published online November 15, 1996
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Nitric oxide, an endothelium-derived relaxing factor, is a selective pulmonary vasodilator. We
have built and settled down the delivery system of nitirc oxide gas inhalation for the first time
in Korea. Two newborn babies delvelped near fatal pulmonary hypertension after surgical repair
of a congenital diaphragmatic hernia. All conventional therapeutic measures failed. So we
decided to attempt to use of nitric oxide gas for... |
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- Original Article
- Congenital cystic diseases of the lung.
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Won Soon Park, Young Pyo Chang, Hee Ju Kim, Young Yull Koh, Jung Hwan Choi, Chong Ku Yun, Joo Hyun Kim
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Clin Exp Pediatr. 1991;34(12):1671-1677. Published online December 31, 1991
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Congenital cystic diseases of the lung (CCDL) is a clinical group of disorders characterized by a
cystic appearance of pulmonary tissue. It can be classified into four distinct categories: 1) Congenital
lobar emphysema (CLE), 2) Congenital cystic adenomatoid malformation (CCAM), 3) Pulmonary
sequeestration (PS), and ^Bronchogenic cyst (BC).
24 patients with CCDL admitted to the Seoul National University Children’s Hospital from January
1984 to June... |
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- Mechanical ventilator care in the newborn infants.
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Young Pyo Chang, Yong Won Park, Won Soon Park, Jung Hwan Choi, Chong Ku Yun
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Clin Exp Pediatr. 1991;34(11):1526-1533. Published online November 30, 1991
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The widespread introduction of mechanically assisted ventilation into the neonatal intensive care
during the 1960s substantially improved the outcome of sick newborn infants, particularly those with
respiratory disorders. We studied the clinical features of 82 neonates, who were treated with
mechanically assisted ventilation in Neonatal Intensive Care Unit (NICU) at Seoul National Univer-
sity Children’s Hospital from January 1986 to August 1989 (the second... |
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- A case of pulmonary vascular air embolism in the newborn.
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Won Soon Park, Beom Soo Park, Hye Kyung Han, Jung Hwan Choi, Chong Ku Yun, Kyoung Mo Yeon, Je Geun Chi
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Clin Exp Pediatr. 1991;34(10):1422-1427. Published online October 31, 1991
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Pulmonary vascular air embolism is a rare, and almost invariably fatal complication of positive
pressure ventilation of newborn infants. There have only been 53 cases described in the world
literature to date.
We have experienced a case of pulmonary vascular air embolism in a premature newborn as a
complication of mechanical ventilation during the course of respiratory distress syndrome.
The pathophysiology and clinical characteristics of... |
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- Clinical Observation on Juvenile Rheumatoid Arthritis.
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Won Soon Park, Kwang Wook Ko
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Clin Exp Pediatr. 1986;29(2):152-162. Published online February 28, 1986
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A clinical observation on 70 patients of juvenile rheumatoid arthritis who were admitted
to S.N.U.H. during the 6 year period from Jan. 1979 to Dec. 1984, was assessed.
The results were as follows;
1) On type classification, systemic type(37.2%) was most frequent, followed by RF negative polyarticular type, pauciarticular type H, RF positive polyarticular type and pauciarticular type I in order of frequency. The... |
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